Unsteady hybrid nanoparticle-mediated magneto-hemodynamics and heat transfer through an overlapped stenotic artery: Biomedical drug delivery simulation

Two-dimensional laminar hemodynamics through a diseased artery featuring an overlapped stenosis was simulated theoretically and computationally. This study presented mathematical model for the unsteady blood flow with hybrid biocompatible nanoparticles (Silver Gold) inspired by drug delivery applications. A modified Tiwari-Das volume fraction adopted nanoscale effects. Motivated magneto-hemodynamics effects, uniform magnetic field applied in radial direction to flow. For realistic behavior, Reynolds’ viscosity formulation represent temperature dependency of blood. Fourier’s heat conduction law assumed generation effects were included. Therefore, governing equations extension Navier–Stokes magneto-hydrodynamic body force The two-dimensional transformed normalized appropriate variables, mild stenotic approximation implemented. strongly nonlinear nature resulting dimensionless boundary value problem required robust numerical method, therefore FTCS algorithm deployed. Validation solutions particular case constant non-magnetic Using clinically hemodynamic data, comprehensive silver, silver-gold mediated comparison between silver nanofluid also included, emphasizing use minimizing hemodynamics. Enhancement parameter decelerated axial region. Colored streamline plots blood, nano-doped presented. simulations relevant diffusion nano-drugs targeted treatment stenosed arterial diseases.